K-562 cells were subjected to SDS PAGE followed by western blot with FNab07538(RUVBL2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab07538(RUVBL2 antibody) at dilution of 1:50
Background
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.