Products
RNF40 antibody
- Product Name
- RNF40 antibody
- Catalogue No.
- FNab07358
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ring finger protein 40
- Alternative Names
- BRE1B antibody, KIAA0661 antibody
- UniProt ID
- O75150
- Observed MW
- 140 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF,IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100; ChIP : 1:50 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07358(RNF40 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis using FNab07358(RNF40 antibody) at dilution of 1:50
Immunofluorescence analysis of MCF-7 cells using FNab07358( RNF40 Antibody) at dilution of 1:50
- Background
- The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
