HL-60 cells were subjected to SDS PAGE followed by western blot with FNab07067(RAC2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab07067( RAC2 Antibody) at dilution of 1:100
Background
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6.