Products
PAK6 antibody
- Product Name
- PAK6 antibody
- Catalogue No.
- FNab06124
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- p21 protein (Cdc42/Rac)-activated kinase 6
- Alternative Names
- PAK5 antibody
- UniProt ID
- Q9NQU5
- Observed MW
- 75 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab06124(PAK6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain cancer using FNab06124(PAK6 antibody) at dilution of 1:100
- Background
- This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
