Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06119(PAK1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer slide using FNab06119( PAK1 Antibody) at dilution of 1:100
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.