OPA3 antibody

Catalogue No.:FNab05995Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
OPA3 antibody
Catalogue No.
FNab05995
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
UniProt ID
Q9H6K4
Observed MW
20 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05995(OPA3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab05995(OPA3 antibody) at dilution of 1:100
Background
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.