Products
OCT4 antibody
- Product Name
- OCT4 antibody
- Catalogue No.
- FNab05963
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- POU class 5 homeobox 1
- Alternative Names
- Oct 3 antibody, Oct 4 antibody, OCT3 antibody, OCT3/4 antibody, OCT4 antibody, Octamer binding protein 3 antibody, Octamer binding protein 4 antibody, OTF 3 antibody, OTF3 antibody, OTF4 antibody, POU class 5 homeobox 1 antibody, POU5F1 antibody
- UniProt ID
- Q01860
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05963( OCT4 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab05963(OCT4 antibody) at dilution of 1:50
Immunofluorescent analysis of Hela cells, using OCT4 antibody FNab05963 at 1:50 dilution.
- Background
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
