HeLa cells were subjected to SDS PAGE followed by western blot with FNab05283(MPI Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab05283(MPI Antibody) at dilution of 1:100
Background
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants.