Products
MGMT antibody
- Product Name
- MGMT antibody
- Catalogue No.
- FNab10100
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- O-6-methylguanine-DNA methyltransferase
- Alternative Names
- MGMT antibody
- UniProt ID
- P16455
- Observed MW
- 22 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:50 - 1:500
Validated Images
Immunohistochemistry of paraffin-embedded human liver cancer using FNab10100(MGMT antibody) at dilution of 1:200
- Background
- Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
