KCNJ3 antibody

Synonyms:GIRK 1 antibody, GIRK1 antibody, KCNJ3 antibody, KGA antibody, KIR3.1 antibody
Catalogue No.:FNab04492Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KCNJ3 antibody
Catalogue No.
FNab04492
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
potassium inwardly-rectifying channel, subfamily J, member 3
Alternative Names
GIRK 1 antibody, GIRK1 antibody, KCNJ3 antibody, KGA antibody, KIR3.1 antibody
UniProt ID
P48549
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse brain were subjected to SDS PAGE followed by western blot with FNab04492(KCNJ3 antibody) at dilution of 1:1000
Background
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.