Products
ILF3 antibody
- Product Name
- ILF3 antibody
- Catalogue No.
- FNab04288
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin enhancer binding factor 3, 90kDa
- Alternative Names
- DRBF antibody, MPHOSPH4 antibody, NF90 antibody
- UniProt ID
- Q12906
- Observed MW
- 95/120 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04288( NF90, ILF3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab04288(NF90, ILF3 antibody) at dilution of 1:100
- Background
- This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
