Products
HLA-G antibody
- Product Name
- HLA-G antibody
- Catalogue No.
- FNab09952
- Size
- 100μg
- Form
- liquid
- Purification
- protein A+G purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 3C12
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- MHC class I antigen G
- Alternative Names
- HLA 6.0 antibody, HLA G antibody, HLA G antigen antibody, HLAG antibody, HLA-G antibody, MHC class I antigen G antibody, MHC G antibody
- UniProt ID
- P17693
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:2000-1:10000; IHC: 1:50-1:200
Validated Images
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09952( HLA-G Antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human placenta tissue slide using FNab09952( HLA-G Antibody) at dilution of 1:200
- Background
- Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
