Raji cells were subjected to SDS PAGE followed by western blot with FNab03785(HCK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab03785( HCK Antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab03785(HCK antibody) at dilution of 1:50
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.