Products
GLRX antibody
- Product Name
- GLRX antibody
- Catalogue No.
- FNab03490
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glutaredoxin (thioltransferase)
- Alternative Names
- GRX antibody
- UniProt ID
- P35754
- Observed MW
- 12 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
SW480 cells were subjected to SDS PAGE followed by western blot with FNab03490(GLRX Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab03490(GLRX antibody) at dilution of 1:100
- Background
- This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
