COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab03064(SQS antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab03064(SQS antibody) at dilution of 1:100
Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.