A431 cells were subjected to SDS PAGE followed by western blot with FNab02667( EGFR Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer slide using FNab02667( EGFR Antibody) at dilution of 1:50
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.