Products
CYP46A1 antibody
- Product Name
- CYP46A1 antibody
- Catalogue No.
- FNab02167
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 46, subfamily A, polypeptide 1
- Alternative Names
- CYP46 antibody
- UniProt ID
- Q9Y6A2
- Observed MW
- 57 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab02167(CYP46A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate using FNab02167(CYP46A1 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
