Coproporphyrinogen oxidase antibody

Synonyms:Coprogen oxidase antibody, Coproporphyrinogen oxidase antibody, Coproporphyrinogenase antibody, COX antibody, CPO antibody, CPOX antibody, CPX antibody, HCP antibody
Catalogue No.:FNab01868Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Coproporphyrinogen oxidase antibody
Catalogue No.
FNab01868
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
coproporphyrinogen oxidase
Alternative Names
Coprogen oxidase antibody, Coproporphyrinogen oxidase antibody, Coproporphyrinogenase antibody, COX antibody, CPO antibody, CPOX antibody, CPX antibody, HCP antibody
UniProt ID
P36551
Observed MW
36 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab01868(CPOX antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab01868(CPOX antibody) at dilution of 1:100
Background
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).