Products
APLP1 antibody
- Product Name
- APLP1 antibody
- Catalogue No.
- FNab00486
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- amyloid beta (A4) precursor-like protein 1
- UniProt ID
- P51693
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00486( APLP1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab00486( APLP1 Antibody) at dilution of 1:50
- Background
- This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
