Products
ALR antibody
- Product Name
- ALR antibody
- Catalogue No.
- FNab00349
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- growth factor, augmenter of liver regeneration
- Alternative Names
- ALR antibody, ERV1 antibody, GFER antibody, Hepatopoietin antibody, HERV1 antibody, HPO antibody, HPO1 antibody, HPO2 antibody, HSS antibody
- UniProt ID
- P55789
- Observed MW
- 23-25 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab00349(GFER antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab00349(GFER antibody) at dilution of 1:100
- Background
- The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
