alpha Adaptin antibody

Synonyms:ADTAA antibody, alpha Adaptin antibody, Alpha adaptin A antibody, Alpha1 adaptin antibody, AP 2 complex subunit alpha 1 antibody, AP2 ALPHA antibody, AP2A1 antibody, CLAPA1 antibody
Catalogue No.:FNab00323Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
alpha Adaptin antibody
Catalogue No.
FNab00323
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
adaptor-related protein complex 2, alpha 1 subunit
Alternative Names
ADTAA antibody, alpha Adaptin antibody, Alpha adaptin A antibody, Alpha1 adaptin antibody, AP 2 complex subunit alpha 1 antibody, AP2 ALPHA antibody, AP2A1 antibody, CLAPA1 antibody
UniProt ID
O95782
Observed MW
108 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00323(AP2A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab00323(AP2A1 antibody) at dilution of 1:100
Background
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.