Products
AKR7A2 antibody
- Product Name
- AKR7A2 antibody
- Catalogue No.
- FNab00266
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
- Alternative Names
- AFAR antibody, AFAR1 antibody, AFB1 aldehyde reductase 1 antibody, AFB1 AR 1 antibody, AFB1 AR1 antibody, AKR7 antibody, AKR7A2 antibody, Aldoketoreductase 7 antibody, SSA reductase antibody
- UniProt ID
- O43488
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00266(AKR7A2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab00266(AKR7A2 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
