Products
AEG-1/MTDH-Specific antibody
- Product Name
- AEG-1/MTDH-Specific antibody
- Catalogue No.
- FNab00189
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- metadherin
- Alternative Names
- 3D3 antibody, 3D3/LYRIC antibody, AEG 1 antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, Metastasis adhesion protein antibody, MTDH antibody, Protein LYRIC antibody
- UniProt ID
- Q86UE4
- Observed MW
- 64 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00189(AEG-1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab00189(AEG-1 antibody) at dilution of 1:200
- Background
- MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
