Products
RGS2 antibody
- Product Name
- RGS2 antibody
- Catalogue No.
- FNab07269
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- regulator of G-protein signaling 2, 24kDa
- Alternative Names
- G0S8 antibody, RGS2 antibody
- UniProt ID
- P41220
- Observed MW
- 24kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab07269(RGS2 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07269(RGS2 antibody) at dilution of 1:50
- Background
- Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
