CD137 antibody

Synonyms:TNFRSF9 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody
Catalogue No.:FNab10476Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CD137 antibody
Catalogue No.
FNab10476
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Tumor necrosis factor receptor superfamily member 9
Alternative Names
TNFRSF9 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody
UniProt ID
Q07011
Observed MW
27 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab10476(CD137 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse spleen tissue slide using FNab10476( CD137 Antibody) at dilution of 1:200
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.