Involucrin antibody

Synonyms:involucrin antibody, IVL antibody
Catalogue No.:FNab04368Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Involucrin antibody
Catalogue No.
FNab04368
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
involucrin
Alternative Names
involucrin antibody, IVL antibody
UniProt ID
P07476
Observed MW
80 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:50-1:500
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab04368(IVL antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skin tissue slide using FNab04368(Involucrin Antibody) at dilution of 1:50
Background
Involucrin is a protein precursor of the epidermal cornified envelope that is assembled in the outermost layers of the epidermis. Involucrin expression is restricted to the suprabasal epidermal layers (spinous and granular layers) during normal keratinocyte differentiation and is a useful marker of terminal differentiation. The predicted MW of involucrin is 68 kDa, while different reports provided variable results ranging from 90-140 kDa.