[Cited FineTest ELISA Kit] Current Research on Implantable Drug Delivery System

FineTest ELISA kit contributes to the research on implantable drug delivery system. The immunoassay is designed to measure IL-1β and PGE2 concentration in serum.

Publication Details
Article Title: A soft implantable energy supply system that integrates wireless charging and biodegradable Zn-ion hybrid supercapacitors
Journal Title: Science Advances
DOI: 10.1126/sciadv.adh8083
IF: 13.6
PMID: 37967195

Abstract:   The advent of implantable bioelectronic devices offers prospective solutions toward health monitoring and disease diagnosis and treatments. However, advances in power modules have lagged far behind the tissue-integrated sensor nodes and circuit units. Here, we report a soft implantable power system that monolithically integrates wireless energy transmission and storage modules. The energy storage unit comprises biodegradable Zn-ion hybrid supercapacitors that use molybdenum sulfide (MoS2) nanosheets as cathode, ion-crosslinked alginate gel as electrolyte, and zinc foil as anode, achieving high capacitance (93.5 mF cm-2) and output voltage (1.3 V). Systematic investigations have been conducted to elucidate the charge storage mechanism of the supercapacitor and to assess the biodegradability and biocompatibility of the materials. Furthermore, the wirelessly transmitted energy can not only supply power directly to applications but also charge supercapacitors to ensure a constant, reliable power output. Its power supply capabilities have also been successfully demonstrated for controlled drug delivery.

Keywords: Alginates, Drug Delivery System, Prostheses and Implants

Immunoassay

FineTest Product Sample Species Detection Target
Rat IL-1β(Interleukin 1 Beta) ELISA Kit(ER1094) serum rat IL-1β
Rat PGE2(Prostaglandin E2) ELISA Kit(ER1800) PGE2

Validated Image

drug delivery system

Figure Source: Sci Adv. 2023 Nov 17;9(46):eadh8083. doi: 10.1126/sciadv.adh8083.