Products
Aurora B antibody
- Product Name
- Aurora B antibody
- Catalogue No.
- FNab00748
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 7E4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aurora kinase B
- Alternative Names
- AIK2 antibody, AIM 1 antibody, AIM1 antibody, ARK 2 antibody, ARK2 antibody, AurB antibody, AURKB antibody, Aurora B antibody, aurora kinase B antibody, Aurora related kinase 2 antibody, Aurora/IPL1 related kinase 2 antibody, IPL1 antibody, STK 1 antibody, STK12 antibody, STK5 antibody
- UniProt ID
- Q96GD4
- Observed MW
- 39-45 kDa
Application
- Tested Applications
- ELISA, WB,IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00748(AURKB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lymphoma tissue slide using FNab00748(AURKB Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- Aurora B(AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011).