Products
ZNF346 antibody
- Product Name
- ZNF346 antibody
- Catalogue No.
- FNab09688
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- zinc finger protein 346
- Alternative Names
- DKFZp547M223 antibody, JAZ antibody, Zfp346 antibody, zinc finger protein 346 antibody, ZNF346 antibody
- UniProt ID
- Q9UL40
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:1000 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
MCF7 were subjected to SDS PAGE followed by western blot with FNab09688(ZNF346 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis using FNab09688(ZNF346 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
