Products

YTHDF1 antibody

Synonyms:C20orf21 antibody, DACA 1 antibody, FLJ20391 antibody, YTH domain family protein 1 antibody, YTH domain family antibody, member 1 antibody, YTHDF1 antibody
Catalogue No.:FNab09572Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
YTHDF1 antibody
Catalogue No.
FNab09572
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
YTH domain family, member 1
Alternative Names
C20orf21 antibody, DACA 1 antibody, FLJ20391 antibody, YTH domain family protein 1 antibody, YTH domain family antibody, member 1 antibody, YTHDF1 antibody
UniProt ID
Q9BYJ9
Observed MW
62 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09572(YTHDF1 antibody) at dilution of 1:500
IP Result of anti-YTHDF1 (IP:FNab09572, 4ug; Detection:FNab09572 1:1000) with mouse brain tissue lysate 2640ug.
Immunohistochemistry of paraffin-embedded human brain using FNab09572(YTHDF1 antibody) at dilution of 1:100
Background
Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).