Products
YBX1 antibody
- Product Name
- YBX1 antibody
- Catalogue No.
- FNab09561
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Y box binding protein 1
- Alternative Names
- BP 8 antibody, CBF A antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, DNA binding protein B antibody, EFI A antibody, Enhancer factor I subunit A antibody, MDR NF1 antibody, NSEP 1 antibody, NSEP1 antibody, Y box binding protein 1 antibody, Y box transcription factor antibody, YB 1 antibody, YB1 antibody, YBX1 antibody
- UniProt ID
- P67809
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09561(YBX1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate using FNab09561(YBX1 antibody) at dilution of 1:100
- Background
- This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.
