YAP1 antibody

Synonyms:65 kDa Yes associated protein antibody, YAP antibody, YAP1 antibody, YAP2 antibody, YAP65 antibody, YKI antibody, Yorkie homolog antibody
Catalogue No.:FNab09559Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
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Product Name
YAP1 antibody
Catalogue No.
FNab09559
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Yes-associated protein 1, 65kDa
Alternative Names
65 kDa Yes associated protein antibody, YAP antibody, YAP1 antibody, YAP2 antibody, YAP65 antibody, YKI antibody, Yorkie homolog antibody
UniProt ID
P46937
Observed MW
70 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09559( YAP1 Antibody) at dilution of 1:1000
IP Result of anti-YAP1 (IP:FNab09559, 3ug; Detection:FNab09559 1:700) with NIH/3T3 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab09559(YAP1 antibody) at dilution of 1:100
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.