Products
XRP2 antibody
- Product Name
- XRP2 antibody
- Catalogue No.
- FNab09990
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- retinitis pigmentosa 2
- Alternative Names
- DELXp11.3 antibody, KIAA0215 antibody, Protein XRP2 antibody, RP2 antibody, TBCCD2 antibody
- UniProt ID
- O75695
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09990(XRP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human intestinal cancer using FNab09990(XRP2 antibody) at dilution of 1:100
- Background
- Acts as a GTPase-activating protein(GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119(or UNC119B). Acts as a GTPase-activating protein(GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
