Products

XRCC4 antibody

Synonyms:DNA repair protein XRCC4 antibody, XRCC4 antibody
Catalogue No.:FNab09554Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
XRCC4 antibody
Catalogue No.
FNab09554
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
X-ray repair complementing defective repair in Chinese hamster cells 4
Alternative Names
DNA repair protein XRCC4 antibody, XRCC4 antibody
UniProt ID
Q13426
Observed MW
45 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab09554(XRCC4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09554(XRCC4 antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab09554(XRCC4 antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.
Background
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.