human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09513(WIPI2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab09513(WIPI2 antibody) at dilution of 1:100
Background
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).