Hela cells were subjected to SDS PAGE followed by western blot with FNab09503(WDR77 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab09503(WDR77 antibody) at dilution of 1:200
Background
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.