Products

VPS37A antibody

Synonyms:ESCRT I complex subunit VPS37A antibody, FLJ32642 antibody, FLJ42616 antibody, HCRP1 antibody, hVps37A antibody, PQBP2 antibody, VPS37A antibody
Catalogue No.:FNab09440Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
VPS37A antibody
Catalogue No.
FNab09440
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
vacuolar protein sorting 37 homolog A
Alternative Names
ESCRT I complex subunit VPS37A antibody, FLJ32642 antibody, FLJ42616 antibody, HCRP1 antibody, hVps37A antibody, PQBP2 antibody, VPS37A antibody
UniProt ID
Q8NEZ2
Observed MW
44 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab09440(VPS37A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse stomach using FNab09440(VPS37A antibody) at dilution of 1:50
Background
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.