anti- Visfatin antibody

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Product Information
Product name

anti- Visfatin antibody

Catalogue No.

FNab09847

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Isotype

IgG2b

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

Nicotinamide phosphoribosyltransferase (NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM) , and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Immunogen Information
Immunogen

nicotinamide phosphoribosyltransferase

Synonyms

1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN

Calculated MW

52 kDa

Application
Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF

Recommended dilution

WB: 1:1000-1:4000; IHC: 1:50-1:500; IF: 1:50-1:500

Uniprot information
Uniprot ID

P43490

Images

anti- Visfatin antibody 1

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09847 (Visfatin antibody) at dilution of 1:200


anti- Visfatin antibody 1

rat heart tissue were subjected to SDS PAGE followed by western blot with FNab09847 (Visfatin antibody) at dilution of 1:2000

Current product's manual: Manual

Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.

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Hotline

027-87384275
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