Products
VEGFR-1/FLT-1 antibody
- Product Name
- VEGFR-1/FLT-1 antibody
- Catalogue No.
- FNab09393
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Alternative Names
- FLT antibody, FLT 1 antibody, FLT1 antibody, FLT-1 antibody, Fms like tyrosine kinase 1 antibody, FRT antibody, sflt1 antibody, Tyrosine protein kinase FRT antibody, VEGF receptor 1 antibody, VEGFR 1 antibody, VEGFR1 antibody, VEGFR-1 antibody
- UniProt ID
- P17948
- Observed MW
- 151 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09393(VEGFR1, FLT1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse lung using FNab09393(VEGFR1, FLT1 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
