Products

UVRAG antibody

Synonyms:DHTX antibody, p63 antibody, UVRAG antibody
Catalogue No.:FNab09352Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
UVRAG antibody
Catalogue No.
FNab09352
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
UV radiation resistance associated gene
Alternative Names
DHTX antibody, p63 antibody, UVRAG antibody
UniProt ID
Q9P2Y5
Observed MW
100 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09352(UVRAG antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab09352(UVRAG antibody) at dilution of 1:100
Background
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.