anti- USP11 antibody

  • Specifications
  • Contact
Product Information
Product name

anti- USP11 antibody

Alternative name

UHX1 antibody, USP11 Antibody

Catalogue No.

FNab09305

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Description

USP11 antibody: Rabbit Polyclonal antibody to USP11

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains(PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome(PubMed:12084015). Cleaves preferentially ‘Lys-6’ and ‘Lys-63’-linked ubiquitin chains. Has lower activity with ‘Lys-11’ and ‘Lys-33’-linked ubiquitin chains, and extremely low activity with ‘Lys-27’, ‘Lys-29’ and ‘Lys-48’-linked ubiquitin chains(in vitro)(PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation(PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks(PubMed:15314155, PubMed:20233726).

Immunogen Information
Immunogen

ubiquitin specific peptidase 11

Synonyms

Deubiquitinating enzyme 11, Ubiquitin thiolesterase 11, UHX1, USP11

Calculated MW

110 kDa

Application
Specificity

Human

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:1000-1:10000; IF: 1:20-1:200

Uniprot information
Gene Name

USP11

Uniprot ID

P51784

Images

anti- USP11 antibody 1

Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab09305(USP11 Antibody) at dilution of 1:50


anti- USP11 antibody 1

A549 cells were subjected to SDS PAGE followed by western blot with FNab09305(USP11 antibody) at dilution of 1:1000

RetailerEnd User





Service

Hotline

027-87384275
var cnzz_s_tag=document.createElement('script'); cnzz_s_tag.type='text/javascript'; cnzz_s_tag.async=true; cnzz_s_tag.charset='utf-8'; cnzz_s_tag.src='https://w.cnzz.com/c.php?id=1253658600&async=1'; var root_s=document.getElementsByTagName('script')[0]; root_s.parentNode.insertBefore(cnzz_s_tag,root_s);