anti- Uromodulin antibody

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Product Information
Product name

anti- Uromodulin antibody

Alternative name

ADMCKD2 antibody, FJHN antibody, HNFJ antibody, MCKD2 antibody, THGP antibody, THP antibody, UMOD antibody, uromodulin antibody, Uromodulin Antibody

Catalogue No.

FNab09294

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Description

Uromodulin antibody: Rabbit Polyclonal antibody to Uromodulin

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721)

Immunogen Information
Immunogen

uromodulin

Synonyms

ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, UMOD, uromodulin

Calculated MW

55-73 kDa

Application
Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP

Recommended dilution

WB: 1:200-1:2000; IHC: 1:20-1:500; IP: 1:200-1:2000

Uniprot information
Gene Name

Uromodulin

Uniprot ID

P07911

Images

anti- Uromodulin antibody 1

Immunohistochemistry of paraffin-embedded human kidney using FNab09294(UMOD antibody) at dilution of 1:50


anti- Uromodulin antibody 1

human heart tissue were subjected to SDS PAGE followed by western blot with FNab09294(UMOD antibody) at dilution of 1:400

Current product's manual: Manual

Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.

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Hotline

027-87384275
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