K562 cells were subjected to SDS PAGE followed by western blot with FNab09258(UNC45A antibody) at dilution of 1:1000
IP Result of anti-UNC45A (IP:FNab09258, 4ug; Detection:FNab09258 1:300) with K-562 cells lysate 3600ug.
Immunohistochemistry of paraffin-embedded human stomach using FNab09258(UNC45A antibody) at dilution of 1:100
Background
Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin(Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen(By similarity).