Products
UCHL1/PGP9.5 antibody
- Product Name
- UCHL1/PGP9.5 antibody
- Catalogue No.
- FNab09218
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)
- Alternative Names
- Neuron cytoplasmic protein 9.5 antibody, PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, Ubiquitin thioesterase L1 antibody, Uch L1 antibody, UCHL1 antibody
- UniProt ID
- P09936
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC：1:100-1:500; IP: 1:1000-1:5000
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab09218(UCHL1 antibody) at dilution of 1:3000
IP Result of anti-UCHL1/PGP9.5 (IP:FNab09218, 4ug; Detection:FNab09218 1:2000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab09218(UCHL1/PGP9.5) antibody at dilution of 1:200
- Background
- UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).
