mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09177( UBE2J2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat liver using FNab09177( UBE2J2 Antibody) at dilution of 1:100
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.