Products
UBE2C antibody
- Product Name
- UBE2C antibody
- Catalogue No.
- FNab09165
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin-conjugating enzyme E2C
- Alternative Names
- DJ447F3.2 antibody, UBCH10 antibody, UBE2C antibody, Ubiquitin carrier protein C antibody, Ubiquitin protein ligase C antibody
- UniProt ID
- O00762
- Observed MW
- 17 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:20 - 1:50
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09165(UBE2C antibody) at dilution of 1:1000
IP Result of anti-UBE2C (IP:FNab09165, 3ug; Detection:FNab09165 1:300) with HeLa cells lysate 2440ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09165(UBE2C antibody) at dilution of 1:50
- Background
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
