HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09152( UBC Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab09152( UBC Antibody) at dilution of 1:100
Background
This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.