Products

UAP56 antibody

Synonyms:ATP dependent RNA helicase p47 antibody, BAT1 antibody, D6S81E antibody, DDX39B antibody, DEAD box protein UAP56 antibody, HLA B associated transcript 1 antibody, Spliceosome RNA helicase BAT1 antibody, UAP56 antibody
Catalogue No.:FNab09142Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
UAP56 antibody
Catalogue No.
FNab09142
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
HLA-B associated transcript 1
Alternative Names
ATP dependent RNA helicase p47 antibody, BAT1 antibody, D6S81E antibody, DDX39B antibody, DEAD box protein UAP56 antibody, HLA B associated transcript 1 antibody, Spliceosome RNA helicase BAT1 antibody, UAP56 antibody
UniProt ID
Q13838
Observed MW
49 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09142(BAT1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09142(BAT1 antibody) at dilution of 1:100
Background
This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.