TSH Beta antibody

Synonyms:CHNG4 antibody, Thyrotropin alfa antibody, Thyrotropin beta chain antibody, Thyrotropin subunit beta antibody, TSH B antibody, TSH BETA antibody, TSHB antibody
Catalogue No.:FNab09807Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TSH Beta antibody
Catalogue No.
FNab09807
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
TSHB
Alternative Names
CHNG4 antibody, Thyrotropin alfa antibody, Thyrotropin beta chain antibody, Thyrotropin subunit beta antibody, TSH B antibody, TSH BETA antibody, TSHB antibody
UniProt ID
P01222
Observed MW
16 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
HT-29 cell lysate were subjected to SDS PAGE followed by western blot with FNab09807(TSHB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse lung tissue slide using FNab09807( TSH beta antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab09807( TSH beta antibody). Blue: DAPI for nuclear staining.
Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.