Products
TRIM6 antibody
- Product Name
- TRIM6 antibody
- Catalogue No.
- FNab08991
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tripartite motif-containing 6
- Alternative Names
- RING finger protein 89 antibody, RNF89 antibody, TRIM6 antibody, tripartite motif containing 6 antibody
- UniProt ID
- Q9C030
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08991(TRIM6 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab08991(TRIM6 antibody) at dilution of 1:50
- Background
- E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
